Technician or Research Associate 80-100%
Job Description
Numab Therapeutics AG is an expanding Swiss biotech company based in Horgen, canton of Zürich. The company is focused on the discovery and development of innovative, antibody fragment-based therapeutics with a focus on inflammation and immuno-oncology. With our breakthrough antibodydiscovery and multi-specifics engineering platform, we engage in proprietary projects as well as collaborative research on behalf of partners in the pharmaceutical industry.
To develop Numab’s innovative proprietary therapeutic pipeline we are looking for a highly motivated and experienced individual for a role as Technician or Research Associate within our Pharmacology and Toxicology team.
In this multi-faceted position, you will contribute to driving Numab’s projects towards and through clinical development. You will be responsible for bioanalytical assessments and exploratory biomarker analyses of our multispecific antibody-derived therapeutic proteins by applying methods from a variety of disciplines.
Your Responsibilities:
- Designing, developing, and validating assays, and performing sample analysis using biological techniques for PK, PD and immunogenicity of antibody-derived proteins following SOPs and guidelines
- High-quality data processing, evaluating results, interpreting data, and drawing relevant conclusions from bioanalytical and biomarker assays to support Numab’s discovery and development projects
- Presentation of experiments within team meetings and company presentations
- Keep abreast with current regulatory and industry practices in bioanalysis for biologics and contribution to continuous improvement of technical capabilities and capacity of the team (e.g. innovative assay development, data analysis and automation)
- Work closely with team members and across functions to outline next steps and help to drive the projects to completion
- General organization of the laboratories, evaluation and acquisition of equipment and consumables
Ideal candidates will have:
- Completed an apprenticeship as a laboratory technician with several years of experience or a higher education in biology, (bio-)chemistry or pharmaceutical sciences
- Industry experience in bioanalytics and demonstrated expertise in developing and validating (GLP/ GCLP, ICH) PK, PD biomarkers and immunogenicity (ADA, NAb) assays and cell-based assays
- Good understanding of immunology
- Initiative, problem solving skills, self-motivation and curiosity
- Highly accurate and team-oriented working style paired with a high sense of quality
- Ability to work on diverse tasks independently
- Refined computer user skills (Windows, MS Office) and excellent communication skills
- Computational and programming experience is a plus (e.g. R or Python)
What we offer:
- A diverse field of activities in a dynamic team with an inspiring, entrepreneurial atmosphere
- Flat hierarchies and short decision-making paths
- The opportunity to take responsibility, help shaping and implementing solutions
- Employment conditions in line with the market, superior pension plan, flexible working time model, and opportunities for further personal development
- Performance-based bonus and participation in the employee stock option plan
- Several fun team events throughout the year
- A workplace near the city of Zurich, overlooking the lake